Synthesis of Amides

You may use these summaries and problems but you may NOT download them for use at another site, nor may you charge for access to them. Copyright Linda M. Sweeting 1997

The following example reactions are organized by type, with references to text chapters. Links within these summaries (which may show up as boxes around reagents) will provide further information about the reagents and their other reactions. Return to Reaction Summary menu for other functional group choices.

Note that products are shown after neutralization: neutralization of products is NOT shown here for simplicity.

Addition / Elimination

+ HCl
Anhydrides react similarly yielding one mole of the acid instead of HCl
McMurry 21.4 24.7, Fessenden 15.3C, Schmid 16.5
Mechanism!
To other reactions of acid chlorides

+ HCl
Anhydrides react similarly yielding one mole of the acid instead of HCl
McMurry 21.4, 24.7, Fessenden 15.3C, Schmid 16.5
Mechanism!
To other reactions of acid chlorides

McMurry 21.5, Fessenden 15.4C, Schmid 16.9
To other reactions of esters

To the main graphical reactions menu.
Last update February 1999.